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How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas
Thu, 05 Dec 2024 11:14:04 GMT
When cell growth gets out of control and malignant cells begin to proliferate, cancer can develop in a process known as tumorigenesis. There are always errors in cell division in every body, but ...
p53 : The Most Frequently Altered Gene in Human Cancers
Sat, 25 Nov 2023 13:58:00 GMT
p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
Fri, 01 Nov 2024 11:58:00 GMT
We used a standard procedure for western blot analyses. We purchased antibodies against total p53 and Ser15-phosphorylated p53 from Transductional Signaling Cell, and antibodies against Bclx and ...