Actualités p53.html
ATM: the p53 booster
Tue, 25 Jun 2024 14:14:00 GMT
The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.
The p53 and RB tumour-suppressor pathways
Thu, 08 Nov 2012 07:23:00 GMT
p53 and RB are at the heart of the two main tumour-suppressor pathways that control cellular responses to potentially oncogenic stimuli. Each pathway consists of several upstream regulators and ...
Carol Prives
Tue, 08 Oct 2024 13:09:00 GMT
Mutation of the p53 tumor suppressor gene is the most frequent lesion detected in cancer. Consequently, understanding the structure and function of the normal p53 protein and how it differs from the ...