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Pharmacological targeting of smoothened receptor cysteine-rich domain by Budesonide promotes in vitro myelination
Sun, 13 Oct 2024 17:00:00 GMT
The lowest-energy and most recurring docking pose shows Budesonide occupying the same lipophilic cleft as cholesterol, delineated by residues L112, I156, V157, I496, and L489 (Supplementary Figure S5) ...