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p53 : The Most Frequently Altered Gene in Human Cancers
Sat, 25 Nov 2023 13:58:00 GMT
p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...
p53 polymorphisms: cancer implications
Thu, 30 May 2024 02:59:00 GMT
p53 lies at the hub of a vast signalling network. Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with ...
The role of p53 in male infertility
Sat, 12 Oct 2024 17:01:00 GMT
The tumor suppressor p53 is a transcription factor involved in a variety of crucial cellular functions, including cell cycle arrest, DNA repair and apoptosis. Still, a growing number of studies ...
Cancer risk linked to an inflammatory bowel disease: Study reveals
Wed, 30 Oct 2024 01:16:00 GMT
The study emphasises on the role of the p53 tumor suppressor gene in the pathogenesis of ulcerative colitis - an inflammatory bowel disease.
L'ICANN81 à Istanbul se penchera sur l'avenir de la gouvernance mondiale de l'Internet
Fri, 01 Nov 2024 04:19:00 GMT
La Société pour l'attribution des noms de domaine et des numéros sur Internet (ICANN) tiendra sa 81e réunion publique à Istanbul, du 9 au 14 novembre 2024, sous l'égide de l'Autorité des technologies ...
Colon cancer risk linked to p53 gene in ulcerative colitis
Thu, 24 Oct 2024 17:00:00 GMT
Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité—Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study ...
tealeave/da-wei-lin-data
Fri, 20 May 2022 17:36:00 GMT
Tumor Suppressor Gene Reactivation: Developing novel approaches for directed drug design, especially in the development of small molecules to reactivate mutant p53 in human cancer. Proteomics & CRISPR ...
Diadem Unveils Novel Findings on Early Alzheimer's Disease Detection Using p53-Specific Antibody at CTAD 2024
Fri, 01 Nov 2024 00:38:00 GMT
Diadem SpA, in partnership with researchers from the University of Texas Medical Branch, led by Prof. Rakez Kayed from the Mitchell Center for Neurodegenerative Disorders, presented groundbreaking ...
Carol Prives
Tue, 08 Oct 2024 13:09:00 GMT
Mutation of the p53 tumor suppressor gene is the most frequent lesion detected in cancer. Consequently, understanding the structure and function of the normal p53 protein and how it differs from the ...
Covalent Modification of p53 by (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one
Sun, 13 Oct 2024 17:00:00 GMT
Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States ...
PMV Pharmaceuticals Reports Third Quarter 2024 Financial Results
Thu, 07 Nov 2024 05:11:00 GMT
Enrollment on track in Phase 2 portion of PYNNACLE clinical trial evaluating rezatapopt as monotherapy in patients with TP53 Y220C and KRAS wild-type advanced solid tumors; more than 75% of sites ...
Natural Phycocyanin/Paclitaxel Micelle Delivery of Therapeutic P53 to Activate Apoptosis for HER2 or ER Positive Breast Cancer Therapy
Thu, 10 Oct 2024 17:00:00 GMT
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