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p53 : The Most Frequently Altered Gene in Human Cancers
Sat, 25 Nov 2023 13:58:00 GMT
p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...
Le "talon d’Achille" du cancer de la prostate ou comment affamer la cellule cancéreuse pour la tuer
Fri, 29 Nov 2024 02:40:00 GMT
Dans les formes les plus avancées du cancer de la prostate, les cellules de la tumeur sont dépourvues du gène TP53 qui est un acteur important des thérapies classiques. Alors que cibler ? Des chercheu ...
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
Fri, 01 Nov 2024 11:58:00 GMT
We used a standard procedure for western blot analyses. We purchased antibodies against total p53 and Ser15-phosphorylated p53 from Transductional Signaling Cell, and antibodies against Bclx and ...